A.E. Pushkareva , I.V. Ponomarev , S.B. Topchiy
The relevance of laser treatment of skin vessel lesions was proved demonstratively to be dependent on the appropriate choice of settings of laser systems. Up now there was clearly accepted the algorithm for the determination of both most relevant and safe modes of laser treatment considering features of the vessel angioarchitectonics of the dysplastic vessel to be targeted with laser irradiation. The relevance of different most used laser systems as pulsed dye laser ( PDL), copper vapor laser (CVL), diode laser and Nd:YAG laser was compared, and the limits of phototherapeutic ranges for each laser system were determined by means of numerical simulation of selective skin vessel heating for various combinations of vessel diameters and the distance of the targeted vessel from the skin surface. The fluences band for selective vessel heating with different laser systems appeared to amount to 6-17, 7 J/cm2 for the CVL, 2-6 J/cm2 for the PDL, 40-100 J/cm2 for the diode laser and 80-170 J/cm2 for the Nd: YAG laser. When using the fluence values exceeding this limit, photodestruction becomes nonselective.
Keywords: Copper vapor laser, pulsed dye laser, skin vascular lesions, vessel heating
Guihong Geng, Shuge YangShuge Yang, Kunxia Wei, Wei Wei, Jing Hu
The model of the molten magnesium alloy with injection device was built to investigate the distribution of SiC particle in the uniform magnetic field. The device included a crucible, a magnetic field generator and a powder feeding tube. According to the L16 (44) orthogonal array, sixteen cases were performed to study the effect of injection speed, the particle diameter, the injection angle and the magnetic field intensity on the particle distribution. The results showed that the injection speed was the first important factor affecting the particle homogenous distribution, subsequently the particle diameter, the injection angle and the magnetic field intensity in order. The optimal process parameters were the injection speed of 5m/s, the particle diameter of 120μm, the injection angle of 300 and the magnetic field strength of 0.5T, in which the uniform distribution of the particle can be well achieved.
Keywords: SiCp /AZ91D composite, SiC particle distribution, magnetic field, numerical simulation, Orthogonal experimental
Robert E. Smith
One of the materials used in stereolithography (STL) is Cyracure ® UVR 6105 (Ultraviolet resistant 6105). When cured, or polymerized, it forms a solid material. The major component of the UVR 6105 pre-polymer is 3,4-epoxycyclohexylmethyl-3,4-epoxycyclohexylcarboxylate (ECMECC). It is less mutagenic than bisphenol A diglycidyl ether (BADGE), which has many industrial uses. Both BADGE and ECMECC can be hydrolyzed in reactions catalyzed by esterase enzymes and by acid in gastric fluid. Both BADGE and its hydrolysis product have very solubility in water and low bioavailability. However, the hydrolysis products of ECMECC are partly soluble in water and act as detergents. As a result, they break up the oily globules of ECMECC, forming micelles. This increases the surface area and exposure of ECMECC to esterases and stomach acid. As a result, UVR 6105 is hydrolyzed further, producing mutagenic products that have relatively high bioavailability. So, workers who handle UCR 6105 should always wear gloves and should wash their hands with soap and water afterwards. Moreover, UVR 6105 may not be the best choice for making devices that go into the human body.
Keywords: 3D printing, stereolithography, Cyracure ® UVR 6105, epoxies, mutagens, cancer
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The journal of "ADVANCED MODELLING AND SIMULATION" is an international, peer-reviewed and Open Access journal published by "Payam Scientific Publishing. This journal publishes original research or review on all areas of modelling and simulation. The main objective is to provide researchers free online access to high-quality articles having outstanding scientific significance .
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|Department of Quantum Radiophysics, P.N. Lebedev Physics Institute, 53, Leninsky Prospect, Moscow, 119991, Russian Federation
Dr. I.V. Ponomarev is currently working at the Department of Quantum Radiophysics, P.N. Lebedev Physics Institute, 53, Leninsky Prospect, Moscow, 119991, Russian Federation
|School of Materials Science and Engineering, Changzhou University, China
Wei Wei is a Professor and Vice dean of School of Materials Science
and Engineering at Changzhou University (CZU), Executive director
of Sino-Russia Joint Laboratory of Functional Nanostructured
Materials, Visiting Scientist at University Vienna (2011), Member of
Editorial Board of Acta Metallurgica Slovaca, Member of Program
Committee of 5th International Symposium of Bulk Nanostructured
Materials (2015). He obtained his Ph. D degree in 2005 at Nanjing
University of Science and Technology (P R China) and joined CZU in
May 2005. He has authored/co-authored more than 70 refereed
journal papers, 4 monographs and books, 15 author's certificates and
patents. His research interest includes: bulk nanostructured metals
(BNM), metal forming and the relationship between microstructure
and mechanical properties.
|Department of Science, Park University, USA
Robert E Smith is an Adjunct Assistant Professor at Park
University, in Parkville, Missouri, USA. He obtained his Ph.D
degree in 1979 from the University of Missouri – Kansas City,
USA. He has authored/co-authored more than 1300 refereed
journal papers, 3 book chapters, and seven books, including his
most recent, ‘Systems Thinking in Medicine and New Drug
Discovery, Volumes One and Two’, published by Cambridge
Scholars Publishing (Newcastle upon Tyne, UK). His research
work has obtained more than 2000 non- self-citations. His
research interest is developing and validating methods to
identify and quantify toxic substances in foods, beverages and
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